- SEC Cleaners
- Second Street Investors LP
- Second Street Wholesalers
- Segal Puppet Theatre & Co
- SENATOR Arlen Specter
- Seslia & Co
- Seven Arts Framing
- Seven Mountains Spirit Fist
- Seventh & Chestnut Assoc
- Sfizzio Restaurant & Bar
- Shaan Enterprises
- Shah & Byler Law Firm
- Shamrock Radio Sales
- Shane Candy Co
- Shannon Fitzpatrick
- Sharla Feldsher Public Relatns
- Sharpshooter Imaging
- Shawmut Design & Constr Inc
- Sheldon Tabb
- Sheppard Corp
- Sheraton Hotel
- Sherick Project Management